S.A.R.M's are nontoxic to the liver and have little effect on blood pressure. This eliminates the need for preloading and on-cycle support supplements. Subsequently, a S.A.R.M cycle will ultimately be less expensive than a traditional AAS/Ph (steroid/prohormone) cycle. The chances of estrogen-related sides and water retention are significantly lower, as well.
The products explained.
DROL - LGD 4033
LGD 4033 a S.A.R.M like Ostarine but 12 times as powerful at only 1/3 the dose! Consequently it is more suppressive to the HPTA (Hypothalamus-Pituitary-Testes-Axis – the system of the hypothalamus, pituitary gland and gonadal glands, which plays a vital role in the development and regulation of the reproductive and immune systems). So, a SERM (selective estrogen receptor modulator) post cycle therapy is recommended.
Where Ostarine is best used in a cutting cycle, LGD has proven itself as a good bulking agent. LGD has a half-life ranging between 24 and 36 hours so daily dosing is optimal.
In a study performed at Boston University, healthy men who were given 1mg of LGD daily gained about 3 pounds in 3 weeks on average. No clinically significant changes were noted in liver function tests, PSA (prostate issue/function tests), hematocrit (testing on the ratio of the volume of red blood cells to the total volume of blood) or ECG (electrocardiogram tests, used to check the heart's rhythm and electrical activity).
IBUTA MK 677 (Ibutamoren)
This is a non-peptidic, orally active and selective agonist of the growth hormone secretagogue (secretion-boosting) receptor. It mimics the action of ghrelin (the hormone that regulates appetite and the distribution and rate of use of energy) in the stomach, raising growth hormone and IGF-1 levels, but does not affect cortisol levels.
Human studies have shown it to increase both muscle mass and bone mineral density. Dosed at 25mg daily, Ibutamoren has been shown to increase IGF-1 levels by 60% in 6 weeks in humans. A 72% increase in IGF-1 levels was seen after 12 months.
MK 677 is non-hormonal and therefore requires no PCT after the cycle is over. It is best utilised in at least a 3 month cycle with dosage increasing each month. The optimal dosing time for MK 677 is at night directly before going to bed. You should start to notice a deeper sleep almost immediately. If you should wake up with numb or tingly hands, do not worry. This is a common side effect of the extra GH in the system.
CARDA GW 501516
This is actually not a S.A.R.M. In fact it is a PPAR Delta Modulator – a selective agonist with a high affinity for the PPAR (peroxisome proliferator-activated receptors - a group of steroid- and thyroid-sensing proteins that control the expression of genes, thereby regulating cellular development and metabolism). This modulation allows the body to utilise more glucose and create more muscle tissue.
CARDA also regulates the various proteins that the body uses for energy. For the user, this means an increase in energy and endurance, and it may also mean an increase in muscle mass. It is also possible that CARDA might have a positive effect on blood pressure and lipid profile.
Dosing is in the 7mg to 21mg range, with 14mg being the "sweet spot". The average GW cycle is typically 4 to 12 weeks. CARDA is non-hormonal and therefore requires no PCT. However, it does stack well with SARMS to further increase fat loss and endurance.
RAD RAD 140
RAD 140 is very new, so there isn't a lot of real world data on it yet. However, it does look very promising, with an impressive anabolic to androgenic ratio of 90:1! This means that users can experience a wealth of muscle building effects without all the associated androgenic side effects.
RAD is powerful enough to limit the effect of testosterone on the prostate and other unwanted areas. It has even been shown to be more anabolic than testosterone, as well. Dosing appears to be in the 4mg to 12mg range, with optimal cycle length being 4 to 6 weeks. Given its shorter half-life (16 hours), RAD needs to be dosed at least twice daily.
This is probably the most well-known S.A.R.M. It is best used to preserve muscle mass while in a caloric deficit. Ostarine can and will suppress your natural testosterone production in longer, higher dosed cycles, so a SERM PCT is needed. Ostarine can also cause gyno in some users, so it is recommended that you have an AI, like Exemestane, on hand.
The average cycle length is 6 to 10 weeks at a dosage range of 10mg to 25mg.
MYO YK-11 and RAD 140
YK-11, also known as Myostine, is rated very highly by professional bodybuilders and strength athletes across the globe. This synthetic and steroidal selective androgen receptor modulator (SARM) has a comparable anabolic activity that is quite similar to anabolic androgenic steroids in nature.
YK-11 was first studied in 2011 by Japanese researcher Yuichiro Kanno. It was found to be a partial agonist of the androgen receptor with gene-selective characteristics. Studies in the past have suggested that YK-11 has better muscle building effects than Dihydrotestosterone (DHT). It has a propensity to act as a Myostatin inhibitor.
What Is A Myostatin Inhibitor?
Myostatin (also called as growth differentiation factor 8) is a protein produced and released by myocytes (a type of cell found in muscle tissue) that act on the autocrine function of muscle cells to inhibit myogenesis: growth and differentiation of muscle cell.
Essentially, Myostatin keeps the body from growing too much muscle. A Myostatin inhibitor like YK-11 inhibits how much of Myostatin is in the body and this allows you to surpass your muscle building and bodybuilding thresholds. In addition to this, YK-11 also has the ability to increase Follistatin, an activin-binding protein, to a great degree. In other words, YK-11 helps the body to produce far significant gains in terms of lean muscle mass that would have been otherwise almost unattainable.
How MYO Works?
MYO attaches itself to the androgen receptor that prompts muscle cells to naturally produce more of anabolic factors. Unlike most SARMs, YK-11 does not come with limited androgenic effects and leads to dramatic muscle growth. In addition to these advantages, MYO also promotes muscle retention, muscle growth, and growth of new muscle cells.
This gene-selective partial agonist of the androgen receptor is well-known for its unique ability to not stimulate any kind of physical interaction between the NTD/AF1 and LBD/AF2 [N-terminal domain (NTD) and activation function (AF); AF1 and AF2 are located within the NTD and the ligand-binding domain (LBD) and regulate the transcriptional activity of the estrogen receptor (ER)] that is required for the complete transactivation of the androgen receptor. YK-11 demonstrates anabolic activity in vitro in C2C12 myoblasts and offers better potency in comparison to dihydrotestosterone (DHT) in this context.
Therefore, it proves out to be a wonderful alternative to everyone who is looking out for a replacement to anabolic steroids that are often fake, sub-standard, and even lead to severe side effect. MYO is also an amazing option for fitness-conscious individuals that want to maintain quality and amount of muscles while keeping away from fat cells.
MYO And Testosterone-Comparison
Testosterone is a critical hormone found in the human body. It works both as an anabolic steroid and a sex hormone.
MYO and Testosterone are quite similar in function and nature. The only underlying difference is that YK-11 is formulated to focus only on specific cells while Testosterone works on most cells in the human body. It is worthwhile to note here that anything beyond the natural levels in the blood can cause undesirable side effects like prostate enlargement. In other words, the use of synthetic testosterone or testosterone injections for a prolonged period is never recommended as the benefits are outperformed by the negatives, especially when testosterone is administered in large quantities.
MYO reacts to specific tissues only and therefore its side effects are zero or almost minimal. Moreover, MYO1 can be administered in an oral form that is both relatively safe and convenient when compared to testosterone injections that can lead to abscess formation, sharing of needles, and pain at the injection sites.
Benefits Of MYO
One of the biggest advantages of YK-11 is that it helps in growing new muscle over those that have already reached the level of genetic limitations. This, in turn, stimulates an increase in the level of muscular corset and hardness.
It also means that heavy muscles of the body are then less susceptible to burnout or deformation even during sessions of cardio training and intense workouts. As a result, workout and training sessions will become longer and more effective and powerful. This will also ensure that the attained results can be easily preserved long after the MYO cycle is over.
The use of MYO is also associated with great advantages, including but not limited to:
No anabolic steroid side effects
Facilitates muscle hardening
Inhibition of Myostatin levels
Increase in Follistatin levels
Better pumps and increased muscular fullness
Increase in muscular strength and size
Lean muscle mass gains without fluid retention
Slows down the ageing process of cells
Improvement of blood circulation
Promotes fat burning
Helps you get rid of stubborn abdominal and visceral fat
Prevents the muscle mass loss during weight loss
Prevents neuronal damage
Stimulates intensive muscle mass growth without a rollback phenomenon
MYO can be added to all kinds of cycles for additional energy and muscle growth
MYO Dosing Recommendations
The recommended dose of YK-11 is 2-5mg (for women) twice and 5-10mg twice a day (for men), preferably with meals, for a period of 6-8 weeks. Some male users even increase the dosages of YK-11 to 20mg a day over the course of a steroid cycle or SARMs cycle with YK-11 though it is always best to start using YK-11 at a lower dosage in the initial stages and find your own sweet spot. A cycle with YK-11 should always end with post cycle therapy to stay protected and retain gains made with this wonderful SARM.
Half-Life Of MYO-Tips And Precautions
MYO, just like most SARMs, are not hepatotoxic since they are non-methylated. Moreover, it is characterised by a high level of oral bioavailability that means MYO can easily be ingested instead of being injected. The half-life of MYO is approximately 5-8 hours.
For maximum effect, most bodybuilders and powerlifters stack YK-11 with Ibutamoren (MK-677). The combination of IBUTA and MYO creates an ideal environment for significant energy, muscle mass, muscle size, and muscle growth gains. MYO is also stacked with RAD for experiencing lightening changes in physique.
MYO is also stacked with DROL (LGD-4033) that is well-known for inducing significant lean muscle mass gains. If you are planning to run RAD and MYO in a cycle of 6-8 weeks, RAD-
Results with MYO are absolutely amazing, to say the least. This is simply because it has anabolic effects on both bone and muscle tissue. It is no wonder that MYO is considered by industry experts and users as the strongest SARM available.
The use of MYO, when complemented with a good diet and intense workouts, can help you easily pack on 10lbs of quality muscle within a period of 6-8 weeks. This muscle gain in such a short period of time actually takes ages to attain in a natural way.
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